Screening Tests

Screening Tests

CST offers the most accurate blood test on the market as well as a whole body MRI scan at our London clinic. For each of our services, you will receive an initial consultation prior to your test or scan following the completion of our medical questionnaire. 

After your appointment, you will receive a detailed report of your results which our in-house doctor will go through in detail. They will answer all your questions and guide you through your options with advice going forward as your personal expert. 

CST offers a clinician-led approach that provides our clients with quality focused support to ensure they are provided with the most suitable options right from the start. Throughout your clinical pathway with us at CST, we provide a dedicated health advice service to listen and answer any questions the clients may have. There is no need for a GP referral as we have our own in-house doctor, who has worked as a consultant radiologist for 12 years. Your appointment can be booked within 24 hours into one of our top central London clinics; Carnaby or Harley Street.

The Cancer Screening Trust believe we are on the cusp of a revolution in cancer treatment, with the potential to save tens of thousands of lives a year. Effective screening programmes are coming to the private healthcare market and forward-looking NHS strategies are starting to think in terms of a national programme. As the only not-for-profit organisation selling Trucheck in the UK, we strive to put some profits back into cancer research. Partnered with the University of Exeter, a number of trials are in discussion particularly focussing on the investigation of a health economic model comparing the use of blood tests with the existing pathways.

Dr Richard Tippett
Clinical Director

  • UCL Bsc in Immunology and Cell Pathology
  • MBBS Medicine and Surgery at St Bartholomew's Hospital Medical School
  • Consultant Interventional Radiologist at Dorset County Hospital for over 12 years
  • Specialises in Interpreting MRI scans of the prostate

Trucheck Tests

What
A prescription blood test that can help detect cancers based on the presence of Circulating Tumour Cells (CTC’s). The test has a 88.2% sensitivity in detection of cancers across all stages and types. Furthermore, it has a 93.1% accuracy in determining the tissue or organ of origin in positive cases. Thus, even early stage cancers are reliably detected. Furthermore, Trucheck specificity is 96.3% in asymptomatic individuals and 95% in individuals with benign tumours.

For Whom
Asymptomatic adult males and females with no previous cancer diagnosis and above the age of 35 years old.

How
Blood samples are evaluated the presence of circulating tumour cells (CTC’s) which may be further analysed to determine the organ or tissue of origin. The blood test appointment takes 20-30 minutes and you will receive your results within 2 weeks.

Why
The Trucheck Intelli blood test is a convenient, accurate and safe way to detect cancer at the earliest stage.

Trucheck Intelli Blood Test - Whole Body

A simple blood test to help find cancer early.

Price: £1,250.00
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Trucheck Intelli Blood Test - Whole Body

Price: £1,250.00

Trucheck is a new blood-based paradigm in multicancer detection. The Intelli test can detect over 70 different types of solid tumours and only requires 25ml blood sample.  The test will provide either a negative or positive result. A negative result suggests that no circulating tumour cells were detected in the given blood sample with 88.2% sensitivity rate. A positive result occurs when CTCs are detected in the given blood sample which is suggestive of malignancy with 99.9% sensitivity. This can be further analysed to determine the tissue or organ of origin. Following your blood draw results, our clinical director will provide you with a consultation and next steps.

CTCs are not detected in cancer-free individuals or those with benign (non-cancerous) conditions. CTCs permit detection of cancers with high sensitivity and enable differentiation between cancer patients and healthy individuals with high specificity.

Download the Trucheck Intelli brochure here.

Hereditary Tests

What 

Hereditary cancer is defined as cancer caused by an inherited genetic variant in a cancer susceptibility gene. Identifying a genetic fault means you have an increased risk of developing cancer, but it doesn’t mean that you have or will be diagnosed with cancer in the future.

For whom 

The Hereditary Cancer Panel is recommended when a genetic cause of cancer is suspected due to clinical features or family history. This includes the following:
  • Early age of onset
  • Multiple primary tumours
  • Multifocal tumour sites
  • Bilateral tumour appearance in paired organs
  • Same type of tumour in first or second-degree relatives or the same tumour type clustering within a family
  • Rare tumour types
  • Rare tumours associated with birth defects
The Hereditary Cancer Panel is available to everyone over 18 years of age, regardless of personal or family history. 


How 

How are samples taken?
The Hereditary Cancer Panel uses genomic DNA (gDNA) extracted from saliva samples. A complete sampling kit containing a sample collection tube and full instructions will be sent to you directly for self-sampling.



How are samples sequenced?
The Hereditary Cancer Panel uses Next Generation Sequencing (NGS), Cell3 target enrichment, and Illumina sequencing to produce large-scale, high-throughput sequencing data that allows the order of nucleotide bases within a genome to be studied. This allows the identification of single nucleotide variants (SNVs), indels, and copy number variants (CNVs).

  • Sensitivity (ability of assay to detect true positive results) was:
    • 100% for SNVs/indels
    • >96% for CNV. 
    • The 95% confidence interval was >98% for SNVs, >90% for indels and >87% for CNVs.
  • Specificity (ability of assay to detect true negative results) >99.99%.
  • Overall positive predictive value was estimated at >97%?
  • Reproducibility 100%

Why 

It is estimated that 5-10% of all cancer cases have a genetic variant that leads to cancer susceptibility. Identifying this allows individuals to find out more about risk management strategies and screening programs specific to their genetic variant which can aid early cancer detection. Therefore, patients and family members can make informed choices about their health plan.

Hereditary Cancer Test

A simple saliva sample using genomic DNA to identify genetic variants associated with increased cancer risk

Price: £575.00
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Hereditary Cancer Test

Price: £575.00

Hereditary cancer is defined as cancer that has been caused by an inherited genetic variant. The Hereditary Cancer Panel involves testing for inherited genetic variants that are associated with an increased cancer susceptibility risk.

The Hereditary Cancer Panel includes 31 different genes and has been expertly curated using current literature and national testing guidelines to maximise clinical actionability, whilst minimising uncertainty. This multi-cancer panel targets genes associated with breast, ovarian, colorectal, prostate, melanoma, and pancreatic cancer.

The full gene list for this panel is shown below:

APC, ATM1, BAP1, BARD1, BMPR1A, BRCA1, BRCA2, BRIP1, CDH1, CDK4, CDKN2A, CHEK22, EPCAM3, HOXB13, MLH1, MSH2, MSH6, MUTYH, NF1, NTHL1, PALB2, PMS24, POLD1, POLE, PTEN, RAD51C, RAD51D, SMAD4, STK11, TP53, VHL

Scans

The blood test and Whole-Body MRI scan are two separate parts of the programme and can be chosen independently.

Why

Depending on the risk assessment of your medical history, family history, and blood test results, we may advise you to have the MRI scan.

What

MRI stands for Magnetic Resonance Imaging. An MRI machine is a large magnet which uses strong magnetic fields to ‘see inside’ your body. It is completely pain-free and requires no injections. The scan extends from the top of your head to the middle of your thighs and takes approximately 1 hour to perform. You will be able to listen to music with special headphones for the duration of the scan. 

A full safety questionnaire will be undertaken prior to your attendance at the scan clinic to exclude any possible contra-indications for the session.

Is the process safe?

Yes. MRI scans have been used since the 1980s and are proven safe. Unlike other medical imaging procedures such as CT (CAT scan) and X-ray, MRIs do not expose you to harmful radiation.

Whole Body MRI Scan

The Whole Body MRI scan looks specifically at these organs: Brain, Head, Abdomen, Pelvis and Spine (whole).

Price: £1,800.00
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Whole Body MRI Scan

Price: £1,800.00

During an MRI scan, the patient lies down on a table that slides through a large tunnel containing powerful magnets. It is this strong magnetic field that allows doctors to see inside your body in a way previously only possible through surgery. It is suitable for every part of your body, including bones, soft tissues and the brain, and is one of the most advanced imaging techniques used to date.

The MRI scan of your head will show us any damage to your:

  • Brain
  • Blood vessels

Based on the results, you may be found to have:

  • Brain tumours
  • Aneurysms
  • Infections
  • Inflammation
  • Haemorrhage

We’ll scan the entire length of your spine. This includes:

  • Cervical spine
  • Thoracic spine
  • Lumbar spine
  • Coccyx
  • Vertebrae
  • Intervertebral discs
  • Spinal cord
  • Other tissues surrounding the spine

The images will be used to diagnose any of the following conditions:

  • Fractures
  • Vertebrae collapse
  • Nerve compression
  • Tumours
  • Herniated discs
  • Improper spine curvature
  • Abdomen

We'll cover an overview of the abdominal organs. This includes:

  • Kidneys
  • Liver
  • Spleen
  • Biliary tract
  • Pancreas (to some degree)
  • Gallbladder
  • Overview of the aorta, renal arteries and lymph nodes

The scan will show any damage that may indicate any of these pathologies:

  • Tumours in your organs
  • Cirrhosis
  • Gallstones
  • Pelvis (Musculoskeletal)

A pelvis MRI scan will show the inner structures of your:

  • Pelvic girdle
  • Muscles and ligaments

You may be diagnosed with any of the conditions below:

  • Fractures
  • Polyps and tumours
  • Infections
  • Osteoarthritis

This makes the scan a very useful screening tool and does not use harmful radiation. The images are reviewed by an experienced clinical radiologist and a full written report is provided to you after a telephone consultation, to explain the results. The reading and reporting of the scan is vital because it is important to know which anomalies need to be examined further and which need not raise any concerns. This is where a human eye will be superior to an AI machine reading.

Trublood Tests

Who
  • To triage symptomatic individuals who have been advised an invasive tissue biopsy to check for malignancy
  • Patients where an invasive biopsy has been inconclusive or inconsistent with clinical observations
  • Suspected metastatic relapse to rule out a new primary cancer.
  • Every Individual who desires a “risk free biopsy”

What
Non-invasive diagnostic biopsy to substitute invasive tissue extraction.

Why
Invasive biopsies are risky, inconvenient, painful, and must be performed in a clinical setting. Trublood sample is a simple 25ml blood draw that can be collected from a patient’s house or office.

How
Circulating tumour cells are isolated from a patient’s blood sample and extensively analysed for diagnosis, prognosis, and theranostics.

Trublood Solid Organ

Trublood® is a revolutionary non-invasive, cost-effective, safe and accurate blood test that can substitute invasive biopsies in most suspected cases of solid tumours and brain tumours.

Price: £1,250.00
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Trublood Solid Organ

Price: £1,250.00

The anxiety, pain, risks, and costs associated with invasive biopsies for cancer diagnosis are substantial. Yet till date, a reliable, safe, and non-invasive test to establish a diagnosis in suspected cases of cancer has not been available. Trublood® is a revolutionary non-invasive, cost-effective, safe and accurate blood test that can substitute invasive biopsies in most suspected cases of solid tumours and brain tumours. Starting with a simple 25ml blood draw, the process involves extremely sensitive, sophisticated and careful isolation and analysis of live circulating tumour cells.

Download Trublood Solid Organ brochure here.

Trublood Prostate

Contact us for more information.

Price: £1,250.00
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Trublood Prostate

Price: £1,250.00

Trublood Lung

Contact us for more information.

Price: £1,250.00
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Trublood Lung

Price: £1,250.00

Trublood Breast

Contact us for more information.

Price: £1,250.00
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Trublood Breast

Price: £1,250.00
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